Submission of 13 Abstracts to the OARSI World Congress 2025

The 2025 OARSI – Osteoarthritis Research Society International World Congress in Incheon, South Korea will be the first in Asia, bringing together the osteoarthritis research community from across the world. Chondrometrics GmbH and its representatives author numerous (n=13) abstracts on a wide range of topics submitted to OARSI 2025:

First Authorships:

FORWARD Study; Felix Eckstein et al.:
– Does treatment efficacy of intra-articular sprifermin on knee osteoarthritis differ between demographic strata – A post-hoc analysis from the FORWARD Phase 2 randomized controlled trial.

MECHSENS Study; Wolfgang Wirth et al.:
– Clinical validation of fully automated cartilage transverse relaxation time (T2) and thickness analysis using quantitative DESS MRI.

ROCELLA (Progress OA) Study; Felix Eckstein et al.:
– Effect of MRI-exclusions on recruitment failure and cartilage thickness change in a clinical trials of advanced knee osteoarthritis.

ROCELLA (Progress OA) Study; Wolfgang Wirth et al.:
– How sensitive are cross-vendor and vendor-specific deep-learning-based segmentation models to longitudinal change in cartilage thickness.

Co Authorships:

MECHSENS Study; Simon Herger et al.;
Univ. Hospital Basel, Switzerland:
– Two-year longitudinal changes in knee cartilage thickness and transverse relaxation time (T2) in ACL-injured versus healthy participants.

KANON Study; Staffan Larsson et al.;
Lund University, Sweden:
– Relationship between knee cartilage thickness and concentrations of biomarkers of matrix metabilism and joint specific inflammation after ACL injury – a longitudinal study.

IMI APPROACH Study; Frank Roemer et al.;
Boston Univ., USA & Univ. Erlangen-Nürnberg, Germany:
– Associations of patellofemoral structural damage with femorotibial cartilage loss over 24 months in Kellgren-Lawrence 2 & 3 knees.

IMI APPROACH Study; Eva Bax et al.;
Univ. Medical Center Utrecht, the Netherlands:
– Radiographic joint space width versus joint line convergence angle: Which one predicts cartilage thickness better?
– Impact of knee rotation on discrepancies between MRI cartilage thickness and mJSW discrepancies between MRI cartilage thickness and mJSW
– The Impact of varus and valgus alignment on knee cartilage quality assessed by MRI.

IMI APPROACH and OAI Study; Mylène Jansen et al.;
Univ. Medical Center Utrecht, the Netherlands
– Phenotyping knee osteoarthritis: comparing pain, liquid biomarkers and joint tissue pathology
– Spontaneous intrinsic cartilage thickening in osteoarthritic knees
– Topography of genuine sex-differences in femorotibial cartilage thickness