REVIEW ARTICLE OSTEOARTHRITIS & CARTILAGE
Published on March 17, 2024 by Chondrometrics-admin
It is with great pleasure and a bit of pride to see our review on 30 years of MRI-based cartilage and bone morphometry in knee osteoarthritis published in the special issue of Osteoarthritis and Cartilage Journal.This exciting journey has taken us from initial “correlation”, i.e. method development with external reference standards for validation to exploring the physiology and pathophysiology of the disease, to qualification studies towards a surrogate endpoint, and finally to interventional “clinical trials”, exploring the structural efficacy of potentially disease modifying OA drugs (DMOADs) on articular tissues.
It has been a great fortune to be able to work on this review with our co-authors from Monash University in Melbourne (Australia): Anita Wluka and Flavia Cicuttini, and receive support of esteemed colleagues, namely Mylène Jansen (Universitair Medisch Centrum Utrecht), Alan Brett (Stryker – Imorphics) and Christoph Ladel (CHL4special consulting).
We are grateful for all the support we received and hope you enjoy reading the article
Felix Eckstein, Wolfgang Wirth
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1 Comment
Felix Eckstein
•It has been a tremendous honor to summarize work on 30 years of cartilage and bone morphometry, together with our colleagues Flavia Cicuttini and Anita Wluka from Monash, Melbourne. Both have shaped the literature over 3 decades, and identifying the “red line” in it, was great enjoyment. With Charles Peterfy and us both having published our first paper on quantitative cartilage analysis in 1994, it was a funny coincidence with the Special Issue of OAC to be dedicated to 30 years of OA research. Very proud to now hold this summary in our hands that also contains a lot of our history in the field.
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