Publication Outlet: Skeletal Radiology

Multifaceted imaging strategies for clinical trials of knee osteoarthritis: a tightly interlinked value and precision chain

Felix Eckstein, Ali Mobasheri, Mikael P Boesen

Skeletal Radiology

Osteoarthritis is a debilitating, whole-organ disease that involves all osteoarticular tissues. No effective treatments have yet been approved by the regulatory agencies for modifying the natural history of this disease and its structural progression....

Evaluation of an automated laminar cartilage T2 relaxation time analysis method in an early osteoarthritis model.

Wolfgang Wirth, Susanne Maschek, Anna Wisser, Jana Eder, Christian F Baumgart...

Skeletal Radiology

Objective: A fully automated laminar cartilage composition (MRI-based T2) analysis method was technically and clinically validated by comparing radiographically normal knees with (CL-JSN) and without contra-lateral joint space narrowing or other sign...

Quantitative measurement of cartilage morphology in osteoarthritis: current knowledge and future directions.

Wolfgang Wirth, Christoph Ladel, Susanne Maschek, Anna Wisser, Felix Eckstein...

Skeletal Radiology

Quantitative measures of cartilage morphology ("cartilage morphometry") extracted from high resolution 3D magnetic resonance imaging (MRI) sequences have been shown to be sensitive to osteoarthritis (OA)-related change and also to treatment intervent...