Perspective
March 20, 2025
Which endpoints should be applied in interventional trials? from single uni-dimensional assessment tailored to a drug’s mechanism of action to multi-component measures and multi-domain composites
Felix Eckstein, Alexander S Chaudhari, David J Hunter, Wolfgang Wirth
Objective: A vast array of structural/imaging and clinical endpoints/outcomes are available today to osteoarthritis epidemiologists or trialists. Which assessments are best suited for...