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Perspective
March 26, 2026

Sex differences in cartilage anatomy, imaging & treatment response

Eckstein F

Osteoarthritis Imaging

Objective: To review findings on sex differences in cartilage anatomy, cartilage imaging, and treatment in osteoarthritis, based on an invited presentation held at the International Workshop of Osteoarthritis Imaging (IWOAI) 2025. Design: A non-systematic literature search (Pubmed) and consultations with experts. Additionally, comparative radiographic joint space width (JSW)...

Perspective
March 20, 2025

Which endpoints should be applied in interventional trials? from single uni-dimensional assessment tailored to a drug’s mechanism of action to multi-component measures and multi-domain composites

Felix Eckstein, Alexander S Chaudhari, David J Hunter, Wolfgang Wirth

Osteoarthritis Imaging

Objective: A vast array of structural/imaging and clinical endpoints/outcomes are available today to osteoarthritis epidemiologists or trialists. Which assessments are best suited for...