Publication Outlet: Osteoarthr Cartil Open

The design of a randomized, placebo-controlled, dose-ranging trial to investigate the efficacy and safety of the ADAMTS-5 inhibitor S201086/GLPG1972 in knee osteoarthritis.

Olivier Imbert, Henri Deckx, Katy Bernard, Ellen van der Aar, Maria Pueyo, Na...

Osteoarthr Cartil Open

Objective: This study aims to assess the efficacy of the anticatabolic 'a disintegrin and metalloproteinase with thrombospondin motif-5' (ADAMTS-5) inhibitor, S201086/GLPG1972, in...

A simple inclusion criteria combination increases the rate of cartilage loss in patients with knee osteoarthritis.

Olivier Imbert, Damien Chimits, Mickaël Guedj, Freddy Lorieau, Katy Bernard, ...

Osteoarthr Cartil Open

Objectives: Selection of patients with KL radiographic grade 2 and 3 is widely used in clinical trials, but this approach could have some limitations. The purpose of this study performed on Osteoarthritis Initiative (OAI)...