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Publication Category: Review

From anatomy to radiology to imaging science: How images become biomarkers and therapeutic evidence

Introduction: Anatomy provides concepts by which form, spatial relationships, and function are brought into context, while radiology extends these concepts into the living. Imaging science asks how biological information is encoded in an imaging signal, converted into a measurement, validated, and used to support therapeutic development and decision-making. Main part: This invited review article follows … Continued

Fundamentals of Osteoarthritis 2026: Imaging

Objective: Osteoarthritis (OA) is the most frequent form of arthritis with major implications on both individual and public health care levels. The field of joint tissue imaging, particularly magnetic resonance imaging (MRI) and computed tomography (CT) with the introduction photon counting technology and weight-bearing CT, has evolved rapidly. This narrative review will provide an introduction … Continued

Advances in cartilage imaging techniques

Articular cartilage is crucial for joint function; however, it has limited regenerative capacity when damaged, a hallmark of many rheumatic diseases. Non-invasive imaging is essential for early diagnosis, therapeutic monitoring and prognostication. MRI remains the reference standard, offering detailed assessment of both morphological and compositional cartilage changes. Technological advances, including high-resolution and compositional MRI techniques … Continued

Magnetic resonance imaging (MRI) transverse relaxation time (T2) for non-invasive assessment of cartilage composition

MRI has transformed medical imaging and research by enabling detailed 3D visualization of soft tissue anatomy. But it also provides insight into biophysical, histological, and mechanical properties via quantitative MRI relaxometry (qMRI). Cartilage transverse relaxation time (T2) has emerged as probably the most robust non-invasive marker of cartilage composition and histological assessment, and of cartilage … Continued

Clinical validation of fully automated (peri-)articular tissue analysis for assessing osteoarthritis progression: a narrative review

Numerous studies have presented fully automated techniques for assessing structural osteoarthritis (OA) progression, with recent work increasingly relying on deep learning (DL)-based methods. The objective of this narrative review was to summarize findings from studies comparing the validity of fully automated methods for assessing progression in (peri-) articular joint tissues with reference measures (e.g., manual … Continued

Osteoarthritis year in review 2020: imaging.

This narrative “Year in Review” highlights a selection of articles published between January 2019 and April 2020, to be presented at the OARSI World Congress 2020 within the field of osteoarthritis (OA) imaging. Articles were obtained from a PubMed s…