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Publication Category: Review

Advances in cartilage imaging techniques

By Chondrometrics-admin

Articular cartilage is crucial for joint function; however, it has limited regenerative capacity when damaged, a hallmark of many rheumatic diseases. Non-invasive imaging is essential for early diagnosis, therapeutic monitoring and prognostication. MRI remains the reference standard, offering detailed assessment of both morphological and compositional cartilage changes. Technological advances, including high-resolution and compositional MRI techniques … Continued

Magnetic resonance imaging (MRI) transverse relaxation time (T2) for non-invasive assessment of cartilage composition

By Chondrometrics-admin

MRI has transformed medical imaging and research by enabling detailed 3D visualization of soft tissue anatomy. But it also provides insight into biophysical, histological, and mechanical properties via quantitative MRI relaxometry (qMRI). Cartilage transverse relaxation time (T2) has emerged as probably the most robust non-invasive marker of cartilage composition and histological assessment, and of cartilage … Continued

Clinical validation of fully automated (peri-)articular tissue analysis for assessing osteoarthritis progression: a narrative review

By Chondrometrics-admin

Numerous studies have presented fully automated techniques for assessing structural osteoarthritis (OA) progression, with recent work increasingly relying on deep learning (DL)-based methods. The objective of this narrative review was to summarize findings from studies comparing the validity of fully automated methods for assessing progression in (peri-) articular joint tissues with reference measures (e.g., manual … Continued

Osteoarthritis year in review 2020: imaging.

By Chondrometrics-admin

This narrative “Year in Review” highlights a selection of articles published between January 2019 and April 2020, to be presented at the OARSI World Congress 2020 within the field of osteoarthritis (OA) imaging. Articles were obtained from a PubMed s…

Articular cartilage in the knee: current MR imaging techniques and applications in clinical practice and research

By Chondrometrics-admin

Magnetic resonance (MR) imaging is the most important imaging modality for the evaluation of traumatic or degenerative cartilaginous lesions in the knee. It is a powerful noninvasive tool for detecting such lesions and monitoring the effects of pharmacologic and surgical therapy. The specific MR imaging techniques used for these purposes can be divided into two … Continued

Quantitative MRI of cartilage and bone: degenerative changes in osteoarthritis

By Chondrometrics-admin

Magnetic resonance imaging (MRI) and quantitative image analysis technology has recently started to generate a great wealth of quantitative information on articular cartilage and bone physiology, pathophysiology and degenerative changes in osteoarthritis. This paper reviews semiquantitative scoring of changes of articular tissues (e.g. WORMS = whole-organ MRI scoring or KOSS = knee osteoarthritis scoring system), … Continued