Publication Category: Review

Articular cartilage is crucial for joint function; however, it has limited regenerative capacity when damaged, a hallmark of many rheumatic diseases. Non-invasive imaging is essential for early diagnosis, therapeutic monitoring and prognostication. MRI remains the reference standard, offering detailed assessment of both morphological and compositional cartilage changes. Technological advances, including high-resolution and compositional MRI techniques … Continued

MRI has transformed medical imaging and research by enabling detailed 3D visualization of soft tissue anatomy. But it also provides insight into biophysical, histological, and mechanical properties via quantitative MRI relaxometry (qMRI). Cartilage transverse relaxation time (T2) has emerged as probably the most robust non-invasive marker of cartilage composition and histological assessment, and of cartilage … Continued

Numerous studies have presented fully automated techniques for assessing structural osteoarthritis (OA) progression, with recent work increasingly relying on deep learning (DL)-based methods. The objective of this narrative review was to summarize findings from studies comparing the validity of fully automated methods for assessing progression in (peri-) articular joint tissues with reference measures (e.g., manual … Continued