Category: Article

We are overly happy that our review on: “Advances in Cartilage Imaging Techniques”, including Felix Eckstein and Wolfgang Wirth as authors, has just been published in Nature Reviews Rheumatology (NRR) https://pubmed.ncbi.nlm.nih.gov/41634466/. This poly-author article covers the following areas: Introduction – MRI technique – semiquantitative MRI – cartilage assessment – cartilage morphometry – high field (3 … Continued

Chondrometrics authors publish a review on clinical validation of automated AI based segmentation of articular tissues in a special issue of Osteoarthritis Cartilage Open, with reference to two recently published original articles by the group. Chondrometrics’ CEO Wolfgang Wirth, and former team and now SAB member Jana Eder, have just published a review in which … Continued

APPROACH (Applied Public-Private Research enabling OsteoArthritis Clinical Headway) was a European Innovative Medicines Initiative (IMI) project designed to improve stratification and prediction of progression in knee osteoarthritis (OA). By integrating imaging, clinical parameters, biochemical markers and machine learning in 300 participants followed over 2 years, the APPROACH consortium established one of the most deeply phenotyped … Continued

ACR Open Rheumatol. 2025 Sep;7(9):e70085 https://pubmed.ncbi.nlm.nih.gov/40977252/ With Jamie Collins from Harvard University and Chondrometrics SAB member as a first author, the 2nd large osteoarthritis biomarker consortium qualification project that was supported by the Foundation of the National Institutes of Health (FNIH), has now been published: The goal was to validate MRI-based prognostic biomarkers using data … Continued

The term virtual is now everywhere: Reality (VR) | Machine (VM) | Assistant (VA) | Network (VPN) | Currency (VC) and many more. But is “Virtual Knee Replacement” (vKR) a cheaper way of surgery without a surgeon, or a new therapy for late-stage osteoarthritis? In their article, just published in Osteoarthritis and Cartilage, Kent Kwoh, … Continued

Double Ace:  A new original study published in Annals of Internal Medicine, a prestigious and influential medical journal that shapes medical practice by its high-impact publications, has highlighted the dual benefit of high tibial osteotomy (HTO) on structure & pain in knee osteoarthritis Birmingham TB, Primeau CA, Moyer RF, Bryant DM, Ma J, Leitch KM, … Continued

Chondrometrics authors publish two concept papers on clinical trials in Skeletal Radiology and Osteoarthritis Imaging (OSTIMA)

Technical and clinical validation of deep-learning based analysis of laminar properties of knee articular cartilage in two models of early osteoarthritis 

The design of a sample rapid magnetic resonance imaging acquisition protocol supporting assessment of multiple articular tissues and pathologies in knee osteoarthritis

Comparisons between unblinded and blinded analysis in the FORWARD RCT treatment phase, and blinded re-analysis of the post-treatment phase